Patolakaturohinyadi Kashayam is a classical Ayurvedic formulation composed of six key herbs—Patola (Trichosanthes dioica), Katurohini (Picrorhiza kurroa), Chandana (Santalum album), Madhusrava (Marsdenia tenacissima), Guduchi (Tinospora cordifolia), and Patha (Cissampelos pareira)—as described in the Ashtanga Hridayam. In Ayurvedic tradition, this kashayam is employed to support healthy skin, liver function, and natural detox pathways, while balancing aggravated Pitta and Kapha doshas. Katurohini is known for its cooling, hepatoprotective, and anti‑inflammatory properties, aiding digestive and liver support. Chandana, Madhusrava, and Patha are traditionally valued for their detoxifying, anti‑itching, and skin‑soothing qualities, while Guduchi adds immune‑supportive and rejuvenating effects.